| 光生物调节作用的在体杀菌策略 |
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| 引用本文： | 朱玲,刘承宜,刘颂豪.光生物调节作用的在体杀菌策略[J].激光生物学报,2008,17(2):278-282. |
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| 作者姓名： | 朱玲 刘承宜 刘颂豪 |
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| 作者单位： | 1. 华南师范大学,激光运动医学实验室,广东,广州,510006
2. 华南师范大学,信息光电子科技学院,广东,广州,510006 |
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| 摘 要： | 世界范围的细菌耐药性呼吁新的抗菌策略,光生物调节作用是有效的候选手段之一。论述了光生物调节作用抗菌效应的研究现状和应用前景。中性粒细胞可以通过吞噬杀菌,也可以通过产生胞外菌阱杀菌。还从活性氧和信号转导所介导的中性粒细胞杀菌作用讨论了光生物调节作用的抗菌机理,为其在临床抗菌中的应用提供理论依据。
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| 关 键 词： | 光生物调节作用 抗菌效应 活性氧 信号转导 |
| 收稿时间： | 2007/8/16 |
Antimicrobial Photobiomodulation Paradigms in vivo |
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| ZHU Ling,LIU Cheng-yi,LIU Song-hao.Antimicrobial Photobiomodulation Paradigms in vivo[J].ACTA Laser Biology Sinica,2008,17(2):278-282. |
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| Authors: | ZHU Ling LIU Cheng-yi LIU Song-hao |
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| Abstract: | Traditional treatment paradigms combating antimicrobial resistance have an been largely unsuccessful,but photobiomodulation(PBM) paradigms might work.The present and future of the research on the antibacterial effects of PBM have been reviewed,respectively.The antibacterial effects of polymorphonuclear neutrophils(PMNs) might be mediated by phagosomes or neutrophil extracellular traps.The antibacterial mechanisms of PBM have been discussed from the viewpoints of the PMN antibacterial effects mediated by reactive oxygen species and signal transduction,which provides a foundation for antibacterial clinic. |
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| Keywords: | photobiomodulation antibacterial effects reactive oxygen species signal transduction |
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