Complete reduction of 2H-pyran-2-one moiety of coumarin and 6-methyl coumarin by Colletotrichum capsici |
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| Authors: | Kumari Gadepalli Narasimha Krishna Ganesh Munuswamy Ramanujam Anitha Rajasekar Sivasubramanian Aravind |
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| Institution: | T R Govindachari Centre for Natural Products, SPIC Science Foundation, Chennai, India. gnkgroup@yahoo.co.uk |
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| Abstract: | The microbial transformation of coumarin (1) and 6-methyl coumarin (2) using Colletotrichum capsici gave 2-(3'-hydroxypropyl) phenol (3) and 2-(3'-hydroxypropyl)-4-methyl phenol (4). The phytopathogenic fungi effectively reduced the 2H-pyran-2-one moiety of both parent coumarins to respective alcohols. |
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