MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data |
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| Authors: | Doniger Scott W Salomonis Nathan Dahlquist Kam D Vranizan Karen Lawlor Steven C Conklin Bruce R |
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| Affiliation: | (1) Gladstone Institute of Cardiovascular Disease, University of California, 94141-9100 San Francisco, CA, USA;(2) Cardiovascular Research Institute, University of California, 94143 San Francisco, CA, USA;(3) Departments of Medicine and Cellular and Molecular Pharmacology, University of California, 94143 San Francisco, CA, USA;(4) Functional Genomics Lab, University of California, 94720 Berkeley, CA, USA; |
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| Abstract: | MAPPFinder is a tool that creates a global gene-expression profile across all areas of biology by integrating the annotations of the Gene Ontology (GO) Project with the free software package GenMAPP . The results are displayed in a searchable browser, allowing the user to rapidly identify GO terms with over-represented numbers of gene-expression changes. Clicking on GO terms generates GenMAPP graphical files where gene relationships can be explored, annotated, and files can be freely exchanged. |
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