Transdetermination of Drosophila imaginal discs cultured in vitro |
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Authors: | Allen Shearn Katherine T Davis Evelyn Hersperger |
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Institution: | Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218 USA |
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Abstract: | Imaginal discs of Drosophila melanogaster undergo transdetermination when cultured in vivo in the abdominal cavity of adult female hosts. We report here that leg discs cultured in vitro, in a recently developed system, also undergo transdetermination. Whether cultured in vivo or in vitro, leg discs produce a similar range of specific transdetermined structures. Moreover, in comparison to discs cultured in vivo, the discs cultured in vitro exhibit a similar correlation between the amount of growth and the total frequency of transdetermination. |
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