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Brain cell surface antigens on embryonal carcinoma cells
Authors:Christo Goridis  Karen Artzt  Kathleen A. Wortham  Melitta Schachner
Affiliation:1. Centre d''Immunologie INSERM-CNRS de Marseille-Luminy, F-13288 Marseille Cedex 2, France;2. Memorial Sloan Kettering Cancer Center, New York, N.Y. 10021, USA;3. Department of Neuroscience, Children''s Hospital Medical Center, Boston, Massachusetts 02115, USA;4. Department of Neurobiology, Universität Heidelberg, D-6900 Heidelberg, GFR;1. Department of Neuroscience, Children''s Hospital Medical Center, Boston, Massachusetts 02115, USA
Abstract:Allo- and heteroantisera against cerebellar tissue from young postnatal mice detect surface antigens on a nullipotent mouse embryonal teratocarcinoma line, F-9. These antigens are operationally identical to the NS-4 and NS-5 antigens described previously. Antigenic specificities are shared with brain, kidney, and sperm.
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