Evidence of a phosphorylated protein specific of human colon carcinoma cells |
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Authors: | N. Munsch H. Raux M.C. Fondanèche P. Burtin |
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Affiliation: | Institut de Recherches Scientifiques sur le Cancer, B.P 8, 94802 Villejuif Cedex France. |
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Abstract: | A phosphorylated 42 kilodalton protein has been detected in HT29 and Caco2, two colonic tumor cell lines, by immunoprecipitation technique. The addition of a differentiating agent such as retinoic acid to the culture medium of the different cell lines induces a 50% reduction of the cellular growth but the 42 K protein remains present. |
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