Norepinephrine and nerve growth factor: Similar proteins phosphorylated in the nuclei of target cells |
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| Authors: | Seiichi Hashimoto Gordon Guroff |
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| Affiliation: | Section on Intermediary Metabolism Laboratory of Developmental Neurobiology National Institute of Child Health and Human Development National Institutes of Health Bethesda, Maryland 20205 USA |
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| Abstract: | Treatment of C6 glioma cells with a β-adrenergic agonist in the presence of radioactive phosphate leads to increased radioactivity in two nonhistone nuclear proteins. These proteins are very similar to those in the nuclei of sympathetic neurons whose phosphorylation is stimulated by nerve growth factor. |
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| Keywords: | SDS sodium dodecyl sulfate PMSF phenylmethylsulfonyl fluoride TCA trichloroacetic acid |
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