The effect of cupric ion on the reoxidation pathway of an IgG1 immunoglobulin |
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| Authors: | Mollie N. Pflumm Fred.K. Friedman Eva Fischer Sherman Beychok |
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| Affiliation: | 1. Department of Biological Sciences and Chemistry, Columbia University New York, New York 10027 USA;2. NIADDK National Institutes of Health, Building 10, Room 9N-307, Bethesda, Maryland 20205 USA |
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| Abstract: | The addition of a 5–10μM of cupric ion to the reoxidation medium of a partially reduced IgG protein results in an altered pathway for covalent reassembly of the molecule. The formation of HL is favored over that of H2 and H2L. |
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| Keywords: | Author to whom all correspondence should be addressed. |
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