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Huntingtin fragments that aggregate go their separate ways |
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| Authors: | DiFiglia Marian |
| Affiliation: | Massachusetts General Hospital, Department of Neurology, Charlestown, MA 02114, USA. |
| Abstract: | N-terminal region of mutant huntingtin forms intranuclear and cytoplasmic aggregates in neurons that may contribute to neuronal death in Huntington's disease. show that different endoprotease-cleaved huntingtin fragments form nuclear and cytoplasmic inclusions. |
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