An automatic system for chromosomal analysis applied to prenatal diagnosis |
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| Authors: | C. Léonard P. Saint-Jean D. Schoëvaërt P. Eydoux S. Girard R. Le Go |
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| Affiliation: | (1) Laboratoire d'Histologie-Embryologie-Cytogénétique, C.H.U. Bicêtre, F-94270 Kremlin-Bicêtre, France;(2) Commissariat à l'Energie Atomique, Institut de la Protection et Sécurité Nucléaire, DPR-SRP, B. P. 6, F-92260 Fontenay-aux-Roses, France;(3) Laboratoire d'Histologie-Embryologie-Cytogénétique, C.H.I., F-78303 Poissy, France;(4) Laboratoire d'Anatomo-Pathologie-Cytogénétique, C. H. Saint-Vincent-de-Paul, 74, avenue Denfert Rochereau, F-75014 Paris, France |
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| Abstract: | Summary Computer-assisted metaphase analysis for prenatal diagnosis can be economically performed by a preexisting hardware-software system. The program can be run by technician-level (i.e., nonspecialist) personnel who can opt for the automatic operational mode for good quality metaphases or for the semimanual mode for problem metaphases (numerous superpositions, artifacts, etc.). The karyotype can be obtained in conversational mode. Hardcopy output is available for all modes. |
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