Mannose-6-p and mannose-1-p in rat brain, kidney and liver.

The approximate concentrations of mannose-6-phosphate and mannose-1-phosphate in female rat brain, kidney and liver are respectively 51, 29 and 99 nmole/g (Man-6-P), and 13, 12, 15 nmol/g (Man-1-P). Intraperitoneal injection of mannose (20 nmol/kg body weight, 15, 30 or 60 min before sacrifice) raises the liver Man-6-P to 0.4 to 4.3 μmol/g and Man-1-P to 100 to 186 nmol/g.