The human calcitonin gene is located on the short arm of chromosome 11 |
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| Authors: | D Przepiorka S B Baylin O W McBride J R Testa A de Bustros B D Nelkin |
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| Institution: | 1. Equipe de Recherches sur le Mécanisme d''Action des Hormones et Neuropeptides Digestifs (INSERM U.55), Hôpital Saint-Antoine, 75012 Paris, France;2. Department of Physiology and Pharmacology, Faculty of Medicine, University of Sherbrooke, Québec, Canada J1H 5N4;3. Ferring Pharmaceuticals AB, Box 30561, S 20062 Malmö, Sweden |
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| Abstract: | By molecular hybridization of human calcitonin cDNA probes to DNA from human-rodent hybrid cells containing identified human chromosomes, we have mapped the human calcitonin gene to the short arm of chromosome 11. This location has been confirmed by in situ hybridization, which further localized the calcitonin gene to region 11p13-15. The significance of this region regarding gene linkage and possible markers for inherited cancers is discussed. |
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