ANTIVIRAL SUBSTANCES FROM CALIFORNIA MARINE ALGAE1 |
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Authors: | D. W. Ehresmann E. F. Deig M. T. Hatch L. H. DiSalvo N. A. Vedros |
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Abstract: | Extracts of 28 species of marine macroscopic algae collected from various coastal habitats of northern California were examined for antiviral activity against a broad spectrum of mammalian viruses. Ten members of Rhodophyta contained substance(s) which caused greater than a 2 log reduction in the infectivity of herpes simplex virus types 1 and 2. In addition, anti-Coxsackie Bs virus activity was detected in extracts of Constantinea simplex Setchell. The physical and chemical properties of the substance in extracts of Farlowia mollis (Harvey and Bailey) Farlow and Setchell and C. simplex indicated the active agent was a structural polysaccharide. |
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Keywords: | anti-herpesvirus substance antiviral substances Constantinea Farlowia herpes simplex virus types 1, 2 polysaccharides red algae |
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