G蛋白及其偶联信号传导途径的研究进展

G蛋白偶联信号传导系统是一类重要的细胞跨膜信号传导途径之一。在有关生化及药理的医学研究中发现许多药剂都是通过G蛋白偶联信号传导途径对动物起作用的。对G蛋白结构与功能的系统研究是新型药剂研制与开发的基础。G蛋白在物种进化过程中具有高度保守性，植物和昆虫中的G蛋白及其偶联组份研究将有助于明确作物抗病虫机理以及昆虫毒理。

The Advancement of G Protein and Coupled Signal Transduction Pathways

G protein coupled signal transduction system is one major transmembrane signaling pathways in cell.Research of biochemistry and pharmacology in medicine showed that a lot of medicines play their role through G protein coupled signaling pathways.Thus,systematic study on G protein structure and functions had very important effects on new medicine producing.In the process of creature evolution,there are highly conserved amino\|acid sequences in G protein.Study on G protein and coupled signal components in plants and insects signaling processes may benefit to determine the mechanism of crop resistance to disease and pest insect and resistant chemicals effect on insect behavior and physiology.This paper reviews the research progress and prospect of practical use in recent studies of G protein and coupled components in animal,insect and plant signaling pathways.