Role of DNA polymerase IV in Escherichia coli SOS mutator activity |
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Authors: | Kuban Wojciech Banach-Orlowska Magdalena Schaaper Roel M Jonczyk Piotr Fijalkowska Iwona J |
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Institution: | Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5A, 02 106 Warsaw, Poland. |
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Abstract: | Constitutive expression of the SOS regulon in Escherichia coli recA730 strains leads to a mutator phenotype (SOS mutator) that is dependent on DNA polymerase V (umuDC gene product). Here we show that a significant fraction of this effect also requires DNA polymerase IV (dinB gene product). |
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