Solitaire AB支架取栓联合动脉溶栓治疗急性缺血性脑卒中的临床疗效

目的:探讨Solitaire AB支架取栓联合动脉溶栓治疗急性缺血性脑卒中的临床疗效。方法:收集2014年8月至2016年8月我院收治的15例急性缺血性脑卒中患者,进行Solitaire AB支架取栓联合动脉溶栓治疗,通过评价患者治疗前后的美国国立卫生研究院卒中量表评分(NIHSS评分)比较治疗效果,通过评价患者随访期间的改良Rankin评分(m RS)和哥拉斯哥昏迷评分(GCS)比较预后情况。结果:15例患者通过动脉溶栓联合1~3次Solitaire AB取栓后,14例患者均达到部分或完全再通,1例患者因生命体征不稳而终止取栓手术,再通率为93.3%。患者出院时NIHSS评分为(4.33±1.45),显著低于术前的(12.93±4.25)(P0.05)。15例患者均通过3个月的术后随访,改良Rankin(m RS)评分均显示良好,其中2例为2分,5例为1分,8例为0分。所有患者均未发生血管再闭塞等相关并发症。结论:Solitaire AB支架取栓联合动脉溶栓治疗急性缺血性脑卒中的临床效果良好且安全性高。

Clinical Efficacy of Mechanical Solitaire AB Stents Thrombectomy Combined with Intra-arterial Thrombolysis in the Treatment of Patients with Acute Ischemic Stroke

ABSTRACT Objective: To investigate the clinical efficacy of mechanical solitaire AB stents thrombectomy combined with intra-ar- terial thrombolysis in the treatment of patient with acute ischemic stroke. Methods: Fifteen patients with acute ischemic stroke admitted into our hospital from August 2014 to August 2016 were treated with mechanical thrombectomy with solitaire AB stents plus intra-arteri- al thrombolysis. The National Institutes of Health Stroke Scale score (NIHSS) of all patients were evaluated before and after treatment to compare the clinical efficacy. The prognosis of patients between two groups were compared via evaluating modified Rankin score (mRS) and gelasijia coma score (GCS). Results: After mechanical thrombectomy with solitaire AB stents plus intra-arterial thrombolysis treat- ment, 14 patients achieved complete or part recanalization, and 1 patient was terminated treatment due to vital signs instability, and the rate of recanalization was 93.3%. The NIHSS score of patients before treatment was 12.93±4.25, which was much higher than that after treatment(4.33±1.45, P<0.05). After follow-up by 3 months, the good mRS scores were obtained in all 18 patients, including 2 patients with mRS score of 2, 5 patients with 1, and 8 patients with 0. Additionally, there was no patient with re-obstruction during follow-up pe- riod. Conclusion: Mechanical thrombectomy with solitaire AB stents combined with intra-arterial thrombolysis had a good capability and safety in the treatment of patients with acute ischemic stroke.