老年心肌梗死患者PCI术后心率变异性的变化及丹参滴丸的临床疗效研究

目的:探究老年心肌梗死患者经皮冠状动脉介入治疗(PCI)术后心率变异性的变化及实施PCI治疗后给予丹参滴丸的临床疗效。方法:收集2015年3月到2016年3月来我院就诊的老年急性心肌梗死患者56例,根据随机数字表法分为试验组及对照组,各28例,对所有患者实施PCI术,术后对照组使用基础药物治疗,试验组使用基础药物治疗联合复方丹参滴丸。比较PCI治疗前后心率变异性的变化及两组患者的心功能。结果:PCI术后,患者测定指标SDNN、SDNN Index及SDANN相对于术前均有升高(P0.05);频域分析指标HF及LF相对于术前均升高,LF/HF比值降低(P0.05)。治疗结束后,两组患者LVEF、SV及CI均明显升高,LVEDD明显降低(P0.05),与对照组相比,试验组患者LVEF、SV及CI较高,LVEDD较低(P0.05)。结论:PCI术能够改善老年心肌梗死患者心率变异性,而复方丹参滴丸对于PCI术后老年心肌梗死患者心功能指标均有明显改善,临床疗效较好。

Study on the Clinical Curative Effect of Danshen Dripping Pill in the Treatment of Heart Rate Variability in Elderly Patients with Myocardial Infarction after PCI

ABSTRACT Objective: To investigate the clinical curative effect of danshen dripping pill in the treatment of heart rate variability in elderly patients with myocardial infarction after PCI. Methods: 56 elderly patients with acute myocardial infarction in our hospital from March 2015 to March 2016 were selected and randomly divided into the control group and the experiment group with 28 cases in each group. All patients underwent PCI, the control group was treated by basic medicine and the experiment group was treated by basic drug therapy combined with compound Danshen dripping pills. The changes of heart rate variability before and after PCI treatment and clinical efficacy of two groups were compared. Results: The SDNN, SDNN Index and SDANN levels were higher postoperative PCI(P<0.05). The Frequency domain analysis index HF and LF levels were higher postoperative PCI (P<0.05), the LF/HF ratio was lower(P<0.05). At the end of treatment, the LVEF, SV and CI levels were higher(P<0.05), the LVEDD was lower(P<0.05). Compared with the control group, the LVEF, SV and CI levels were higher(P<0.05), the LVEDD was lower(P<0.05). Conclusion: PCI could improve the heart rate variability in elderly patients with myocardial infarction, and compound Danshen dripping pills significantly improved cardiac function of elderly patients with myocardial infarction after PCI.