微创经皮椎体成形术治疗脊柱转移性肿瘤的临床疗效分析

目的:探讨微创经皮椎体成形术治疗脊柱转移瘤的临床疗效及安全性。方法:选取我院收治的60例脊柱转移瘤患者并随机分为两组,观察组(30例)行微创经皮椎体成形术治疗,对照组(30例)行开放性手术治疗。比较两组患者术后12、24、48 h的VAS评分、镇痛次数,术前及术后24、48 h的血清C-反应蛋白(CRP)水平,术前及术后3、6个月的Prolo评分。结果:术后12、24、48 h,两组患者的视觉模拟评分法(VAS)评分逐渐下降,且观察组VAS评分均显著低于对照组(P0.05),术后镇痛次数也明显少于对照组(P0.05)。术后24、48 h,两组患者血清CRP水平均明显低于术前,且观察组血清CRP水平显著低于对照组(P0.05)。术后3、6个月,两组患者的Prolo评分均较术前明显提高,且观察组Prolo评分显著高于对照组(P0.05);随访3个月期间,两组并发症的发生情况相比差异无统计学意义(P0.05)。结论:微创经皮椎体成形术可以明显减轻脊柱转移性瘤的疼痛,患者日常生活能力恢复较好,且安全性高。

Analysis of the Clinical Effect of Minimally Invasive Percutaneous Vertebroplasty on the Spinal Metastatic Tumors

ABSTRACT Objective: To discuss the efficacy and safety of minimally invasive percutaneous vertebroplasty in the treatment of spinal metastatic tumors. Methods: 60 patients with spinal metastatic tumors were selected and randomly divided into two groups. The control group(30 cases) was given open operation and the observation group(30 cases) was given minimally invasive percutaneous vertebroplasty. The VAS scores at 12 h, 24 h, 48 h after operation, the analgesia, serum CRP level before and after operation, incidence of complications during 3 months follow-up were compared between two groups. Results: The VAS scores of both groups at 12 h, 24 h, 48 h postoperation were gradually decreased. The VAS scores of observation group was lower than those of the control group(P<0.05). The postoperative analgesia of observation group were significantly lower than those of the control group(P<0.05). At 24 h, 48 h after operation, the serum CRP levels were lower than those before operation(P<0.05). The serum CRP levels of observation group were lower than those of the control group (P< 0.05). At 3 months, 6 months after operation, the Prolo score was increased in both groups. The Prolo score of observation group was higher than that of the control group (P<0.05). During 3 months follow-up, there was no significant difference between two groups(P>0.05). Conclusion: Minimally invasive percutaneous vertebroplasty could significantly reduce the pain of spinal metastases with better prognosis. It could promote the living ability with high safety.