中医针药联合治疗结直肠癌患者术后胃肠功能障碍的疗效观察

目的:观察中医针药联合对结直肠癌患者术后胃肠功能恢复的影响。方法:回顾性收集2010年5月至2016年5月88例接受肠癌根治性手术患者的临床资料,根据术后治疗方式不同分为4组:常规组30例,针灸组20例,中药组22例,针药联合组16例。对比各组患者术后胃肠功能的客观指标:肠鸣音恢复时间、肛门排气排便时间,及实验室指标;血清胃动素(MOT)和生长抑素(SS)水平,并评价各组患者术后总疗效。结果:4组患者肠鸣音恢复时间、肛门排气时间、排便时间及血清MOT及SS水平组间比较均存在统计学差异(P0.05),针药联合组肠鸣音恢复时间、肛门排气时间、排便时间均低于其他3组,针灸组及中药组亦低于常规组,差异均有统计学意义(P0.05);针药联合组血清MOT及SS水平均高于其他3组,针灸组及中药组亦高于常规组,差异均有统计学意义(P0.05)。针灸组、中药组及针药联合组总有效率均高于常规组,针药联合组亦高于针灸组及中药组,差异均有统计学意义(P0.05)。结论:中医针药联合对结直肠癌患者术后胃肠功能障碍的治疗具有显著作用。

Curative Effect Observation of Acupuncture Combined with Chinese Medicine in Treatment of Postoperative Gastrointestinal Dysfunction of Colorectal Cancer Patients

ABSTRACT Objective: To observe the effect of acupuncture combined with chinese medicine on postoperative gastrointestinal function recovery in patients with colorectal cancer. Methods: Retrospective collected the clinical data of 88 patients with colorectal cancer who received radical surgery from May 2010 to May 2016, all patients were divided into 4 groups according to the treatment methods: the conventional group (30 cases), acupuncture group (20 cases), traditional chinese medicine group (22 cases) and acupuncture combined with medicine group (16 cases). Compared the objective index of postoperative gastrointestinal function: the recovery time of bowel sound, anal exhaust and defecation time, and laboratory indexes, include serum motilin (MOT) and somatostatin (SS) levels, then evaluated the overall curative effect of each group. Results: The recovery time of bowel sound, anal exhaust time, anal defecation time and serum MOT and SS levels between were compared between 4 groups of patients were statistically significant differences (P<0.05),the recovery time of bowel sound, anal exhaust time, anal defecation time of acupuncture combined with medicine group were lower than the other 3 groups, acupuncture group and traditional Chinese medicine group were also lower than the conventional group, the difference was statistically significant (P<0.05). The serum MOT and SS levels in acupuncture combined with medicine group were higher than the other 3 groups,acupuncture group and traditional Chinese medicine group were also higher than the conventional group,the difference was statistically significant (P<0.05). The total effective rate of acupuncture group, traditional Chinese medicine group and acupuncture combined with medicine group were higher than that of conventional group, acupuncture combined with medicine group was higher than acupuncture group and traditional Chinese medicine group, the difference was statistically significant (P<0.05). Conclusion:Traditional chinese medicine combined with acupuncture has a significant role in patients of colorectal cancer with postoperative gastrointestinal dysfunction.