不同治疗方式对冠心病合并心脏瓣膜炎患者血清炎性反应的影响

目的:比较不同治疗方式对冠心病合并心脏瓣膜炎的临床指标、生活质量及血清炎性反应的影响。方法:选取2014年2月~2016年6月期间于本院进行治疗的64例冠心病合并心脏瓣膜炎患者为研究对象,将其随机分为对照组和观察组每组各32例,对照组进行常规的药物治疗,观察组则进行外科手术治疗,然后将两组患者治疗前后的心脏功能指标、生活质量及血清炎性指标进行比较。结果:治疗前两组患者的心脏功能指标、生活质量及血清炎性指标比较,P均0.05,而治疗后观察组的心脏功能指标、生活质量及血清炎性指标均显著地好于对照组,P均0.05,均有显著性差异。结论:外科手术对冠心病合并心脏瓣膜炎患者血清炎症因子水平及生活质量具有积极的改善作用,适于临床进一步推广应用。

Influence of Different Treatment Methods for Serum Inflammatory Reactions of Patients with Coronary Heart Disease and Heart Valve

ABSTRACT Objective: To compare the influence of different treatment methods for the clinical indicators, life quality and serum inflammatory reactions of patients with coronary heart disease and heart valve disease. Methods: 64 patients with coronary heart disease with heart valve disease in our hospital from February 2014 to June 2016 were selected and randomly divided into control group and observation group, with 32 cases in each group. The control group was treated with conventional drugs, and the observation group was treated with surgery. The cardiac function indexes, life quality and serum inflammatory indexes of two groups before and after the treatment were compared. Results: When the cardiac function indexes, life quality and serum inflammatory indexes of two groups before the treatment were compared (P>0.05). The cardiac function indexes, life quality and serum inflammatory indexes of observation group after the treatment were all significantly better than those of control group, and the differences were all significant (P<0.05). Conclusion: The surgery has more active in improving clinical indicators, life quality and serum inflammatory reaction of patients with coronary heart disease with heart valve disease, so it is more suitable to these patients.