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颅内血管介入治疗缺血性脑血管病的疗效及预后分析
引用本文:陈斌,金林,张冬子,行治国,郝璞珩,闫志丰,张滟.颅内血管介入治疗缺血性脑血管病的疗效及预后分析[J].现代生物医学进展,2017,17(6):1131-1134.
作者姓名:陈斌  金林  张冬子  行治国  郝璞珩  闫志丰  张滟
作者单位:西安医学院第一附属医院神经外科;西安交通大学医学院第二附属医院耳鼻喉头颈外科
摘    要:目的:探讨颅内血管介入治疗对缺血性脑血管病的临床疗效并分析预后效果。方法:选取2012年6月至2016年6月在我院接受治疗的缺血性脑血管病患者85例,根据患者治疗方式的不同分为观察组43例和对照组42例,其中观察组患者给予血管内支架植入治疗,对照组患者则给予常规药物治疗。观察两组治疗前、后血管收缩期峰流速(Vs)、舒张末期流速(Vd)情况,并比较治疗前、治疗6个月、1年后美国国立卫生院卒中量表(NIHSS)评分以及患者预后情况。结果:治疗后观察组病变血管Vs、Vd均显著低于对照组、治疗前(P0.05)。治疗6个月、1年后观察组NIHSS评分均显著低于对照组、治疗前(P0.05)。治疗1年后观察组脑梗塞与短暂性脑缺血发作率以及病死率均显著低于对照组(均P0.05)。结论:颅内血管介入治疗缺血性脑血管病的疗效显著,可有效促进患者神经功能恢复,同时降低脑血管病事件的发生率及病死率。

关 键 词:介入治疗  缺血性脑血管病  疗效  预后

Analysis of Curative Effect and Prognosis of Intracranial Vascular Interventional Therapy for Ischemic Cerebrovascular Disease
Abstract:Objective:To study the curative effect and prognosis of intracranial vascular interventional therapy for ischemic cerebrovascular disease.Methods:85 patients with ischemic cerebrovascular disease who were treated in our hospital from June 2012 to June 2016 were selected, which were divided into observation group with 43 cases and control group with 42 cases according to the different methods of treatment. The control group was given routine drug treatment, the observation group was treated with endovascular stenting. The Vs and Vd of the lesions in the two groups were compared before and after treatment, the National Institutes of Health Stroke Scale (NIHSS) score and the prognosis of patients before treatment and 6 months and 1 year after treatment were compared.Results:After treatment, the Vs and Vd of the lesions in the observation group were significantly lower than before treatment and those in the control group (p<0.05). After 6 months and 1 year, the NIHSS score of the observation group was significantly lower than that of the control group and before treatment (P<0.05). After 1 year of treatment, the incidence of cerebral infarction and transient ischemic attack and fatality rate in the observation group were significantly lower than those in the control group (all P<0.05).Conclusion:The curative effect of intracranial vascular interventional treatment on ischemic cerebrovascular disease is significant, which can effectively promote the recovery of neurological function and reduce the incidence and mortality of cerebrovascular disease.
Keywords:Intervention treatment  Ischemic cerebrovascular disease  Curative effect  Prognosis
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