抗体信息数据库

抗体是介导体液免疫的重要效应分子。近年来，随着治疗性抗体药物不断上市及其临床应用范围不断拓宽，治疗性抗体已成为生物制药的产业支柱。另一方面，随着抗体相关的基础研究日益深入和抗体序列、结构、功能表位等相关数据大量涌现，作为抗体数据管理、搜索与利用的重要工具，抗体资源库也层出不穷并得到长足发展，在相关的研究、开发、生产与销售中发挥日益重要的作用。本文对包括Kabat、IMGT、abYsis等在内抗体信息数据库进行介绍。

Antibody Information Databases

The antibody is an important type of immunoglobulin that mediates humoral immunity. In recent years antibody drugs have emerged in the worldwide pharmaceutical market. With more therapeutic antibody entering the market and with their widening clinical applications, they have become the pillar of bio pharmaceutical industry. The antibody information database is an important tool to manage, search and use antibodies. With the deepening of antibody research and the emergence of antibody sequences, structures, functional epitopes and other related data, antibody information databases are successively developed and implemented, and continuously playing an important role in the antibody research, development, production and sale. Here we introduce several antibody information databases, such as Kabat, IMGT, abYsis and hope to promote innovation and development for antibody resources.