芪苈强心胶囊联合比索洛尔对老年心力衰竭患者的疗效

目的:研究芪苈强心胶囊联合比索洛尔对老年心力衰竭患者的临床疗效。方法:选择2015年6月~2016年6月在我院进行诊治的老年心力衰竭患者126例,随机分为两组,对照组给予芪苈强心胶囊,观察组在对照组基础上加用比索洛尔。治疗3个月后,比较两组的疗效,以及治疗前后的血压、心率、6 min步行最大距离、脑钠肽水平;采用超声心动图检测两组的左心室舒张末期容积、左心室射血分数、左心室短轴缩短率和左心室收缩末期容积。结果:观察组的有效率为92.06%(58/63),明显高于对照组的73.02%(46/63)(P0.05);治疗后两组血压无明显变化(P0.05),心率和脑钠肽水平明显降低(P0.05),6 min步行最大距离明显增加(P0.05),且观察组明显优于对照组(P0.05);两组的左心室射血分数明显降低(P0.05),左心室舒张末期容积、左心室短轴缩短率和左心室收缩末期容积明显升高(P0.05),且观察组明显优于对照组(P0.05)。结论:芪苈强心胶囊联合比索洛尔能有效改善老年心力衰竭患者的心功能,具有较好的临床疗效。

Effect of Qiliqiangxin Capsule Combined with Bisoprolol on Elderly Patients with Heart Failure

ABSTRACT Objective: To study the effect of Qiliqiangxin capsule combined with bisoprolol on elderly patients with heart failure. Methods: 126 cases of elderly patients with chronic heart failure who were treated in our hospital from June 2015 to June 2016were selected and divided into two groups randomly, the patients in control group were treated with Qiliqiangxin capsule, and the patients in observation group were treated with Qiliqiangxin capsule combined with bisoprolol. The curative effect, blood pressure, heart rate, 6min walking maximum distance, brain natriuretic peptide levels, left ventricular end diastolic volume, left ventricular ejection fraction, left ventricular short axis shortening rate, and left ventricular end systolic volume of the two groups were compared. Results: The effective rate of the observation group was 92.06 %(58/63), significantly higher than 73.02 %(46/63) of the control group(P<0.05); after treatment, there was no significant change in blood pressure of two groups(P>0.05), the heart rate and brain natriuretic peptide levels of two groups were significantly lower (P<0.05), 6 min walking distance of two groups were significantly increased (P<0.05), and it was significantly better in the observation group than that of the control group (P<0.05); the left ventricular ejection fraction was decreased significantly (P<0.05),and left ventricular end diastolic volume, left ventricular short axis shortening rate, and left ventricular end systolic volume was increased significantly (P<0.05), and it was significantly better in observation group than that of the control group (P<0.05). Conclusion: Qiliqiangxin capsule combined with bisoprolol can effectively improve the cardiac function in elderly patients with heart failure, has good clinical efficacy.