冠心病患者胰岛素抵抗程度的影响因素分析

目的:分析冠心病患者胰岛素抵抗程度的影响因素。方法:选择我院收治的冠心病住院患者166例,根据胰岛素抵抗指数(HOMA-IR)水平将其分成四组。A组:HOMA-IR≤1.53(n=36);B组:1.53HOMA-IR≤3.46(n=30);C组:3.46HOMA-IR≤5.13(n=36);D组:HOMA-IR≥5.14(n=64)。检测和比较各组一般临床资料和相关生化指标的差异,并进一步分析影响冠心病患者胰岛素抵抗程度的危险因素。结果:C、D组腰围、空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、低密度脂蛋白胆固醇(LDL-C)均高于A、B组;D组空腹胰岛素(INS)均高于A、B组,B、C组INS、LDL-C均高于A组;D组体质量、TC高于A组。上述差异均有统计学意义(P0.05)。多因素分析结果显示BMI、腰臀比(WHR)、FBG、INS、TC、HDL-C均是HOMA-IR的影响因素(P0.05)。结论:体重、腰围、FBG、2h PBG、INS、TC、HDL-C的上升均为加重冠心病患者胰岛素抵抗程度的危险因素。

Analysis of the Distribution Characteristics of Various Risk Factors in Patients with Coronary Heart Disease in Patients with Different Levels of Insulin Resistance

Objective:To study the distribution characteristics of multiple risk factors in patients with coronary heart disease in patients with different levels of insulin resistance.Methods:166 cases of hospitalized patients with coronary heart disease in our hospital, according to insulin resistance index (HOMA-IR) level will be divided into four groups: group A: HOMA-IR was less than or equal to 1.53 (n=36); group B: 1.53 < HOMA-IR was less than or equal to 3.46 (n=30); group C 3.46 < HOMA-IR was less than or equal to 5.13 (n=36); group D: HOMA-IR was more than or equal to 5.14 (n=64). Used the stable model assessment insulin resistance level of coronary heart disease risk factors distribution.Results:C and D group''s waist circumference, FBG, 2hPBG, LDL-C were higher than B, D group INS were higher than B, B group, INS, C group LDL-C, D group, A group, TC higher than A group. The difference was statistically significant (BMI, WHR, INS, TC, HDL-C, HOMA-IR) were statistically significant (P<0.05). Weight, waist circumference, 2hP- BG, TC, HDL-C, INS were increased in patients with coronary heart disease and insulin resistance in hospitalized patients with FBG.Conclusion:Body weight,waist circumference, FBG, 2hPBG, INS, TC, and HDL-C are all increased in patients with coronary heart disease and insulin resistance.