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Identification of Significant Variation in the Composition of Lipophosphoglycan-like Molecules of E. histolytica and E. dispar1
Authors:Susan Moody  Steven Becker  Yael Nuchamowitz  David Mirelman
Abstract:The lipophosphoglycan-like (LPG-like) molecules of E. histolytica virulent strains are clearly distinct from those of the avirulent E. histolytica and E. dispar strains. Abundant ‘LPG’ levels are apparently limited to virulent strains, while lipophosphopeptidoglycans (‘LPPG's) are common to both virulent and avirulent strains of E. histolytica and E. dispar. It is therefore conceivable that ‘LPPG’ performs a function that is essential to survival within the host, while the ‘LPG’ performs a more specific function related to virulence.
Keywords:Adherence  amebiasis  cytotoxicity
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