|
|||||
|
|
Development of a biosensor assessing SARS-CoV-2 main protease proteolytic activity in living cells for antiviral drugs screening |
|
| Authors: | Yuan Zhang Chunjie Li Xianliang Ke Dan Luo Yan Liu Quanjiao Chen Hanzhong Wang Xiaohui Song Zhenhua Zheng |
| Abstract: | Highlights: The biosensor reported in our study can monitor SARS-CoV-2 Mpro activity in living cells instead of in vitro solutions. The biosensor reported in our study is sensitive and easy to operate. It is suitable for high-throughput screening. It has the potential to be used in small animal models. |
| Keywords: | , , , , |
| 点击此处可从《中国病毒学》浏览原始摘要信息 | |
| 点击此处可从《中国病毒学》下载免费的PDF全文 | |