大豆蛋白源性肽调节糖脂代谢机制研究进展

大豆蛋白源性肽是大豆蛋白质经酸法或酶法水解后分离精制而得到的多肽混合物，是植物蛋白源性肽的重要来源，大豆蛋白源性肽通过抑制肠道胆固醇吸收、与胆固醇的相互作用、调节胆固醇代谢相关基因（用于降低胆固醇）、甘油三酯代谢相关基因、二肽基肽酶Ⅳ和葡萄糖代谢相关基因，在降低胆固醇、降低甘油三酯、抗肥胖、抑制脂肪酸合成酶和抗糖尿病等代谢调节方面具有重要作用。综述了大豆蛋白源性肽在体内外改善脂质和糖代谢方面的生理功能，并对大豆蛋白源性肽的前景进行了展望，以期为大豆蛋白源性肽的研究与应用提供参考。

Progress on the Mechanism of Soybean Protein Derived Peptides Regulating Glucose and Lipid Metabolism

Soybean protein derived peptides is a peptide mixture obtained by separating and refining soybean protein through acid or enzymatic hydrolysis. It is an important source of plant protein derived peptides. Soybean protein derived peptides can inhibit intestinal cholesterol absorption， interact with cholesterol， regulate cholesterol metabolism related genes （used to reduce cholesterol）， triglyceride metabolism related genes， dipeptidyl peptidase Ⅳ and glucose metabolism related genes， it plays an important role in reducing cholesterol， triglycerides， anti-obesity， inhibiting fatty acid synthase and anti-diabetes and other metabolic regulation. This paper reviewed the physiological functions of soybean protein derived peptides in improving lipid and sugar metabolism in vitro and in vivo， and forecasted the prospects of soybean derived peptides， which was expected to provide reference for the research and application of soybean proteinderived peptides.