| Abstract: | The results obtained in the study of the main biological properties of 9 E. coli strains, serogroup O139:K., isolated from monkeys at the Sukhumi monkey breeding colony and yielding the positive result in Sereny's keratoconjunctival test are presented. For the first time E. coli of serovar O139:K.:431 were isolated; these organisms differed from reference strain O139K82:H1 in their enzymatic activity, in the partial composition of O-antigen and in their capacity for inducing experimental keratoconjunctivitis. The isolation of the above-mentioned cultures from monkeys with diagnosed acute intestinal diseases of unclear etiology, both during the life of the animals and in the process of autopsy, from a monkey having had contacts with sick animals in the focus of clinical dysentery, and from monkey subjected to prophylactic examination, as well as the pathogenicity of these strains for guinea pigs, evaluated on the keratoconjunctivitis model, suggest their probable etiological role in E. coli infection in primates and make it possible to regard them as the invasive variants of E. coli, serogroup O139:K.. |
