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Molecular study of genes involved in virulence regulatory pathways in Bacillus anthracis vaccine strain "Carbosap" |
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| Authors: | La Rosa Giuseppina Muscillo Michele Sali Michela De Carolis Elena Marianelli Cinzia Ciuchini Franco Fasanella Antonio Adone Rosanna |
| Affiliation: | Istituto Superiore di Sanità, Environmental and Primary Prevention Department, Viale Regina Elena 299, 00161, Rome, Italy. giuseppina.larosa@iss.it |
| Abstract: | This study investigated the genetic bases of attenuation in the Bacillus anthracis vaccine strain "Carbosap" used in Italy against anthrax in cattle and sheep. Twelve genes involved in virulence regulatory pathways underwent sequence analysis in comparison with a B. anthracis virulent strain. |
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