Monomers for Oligonucleotide Synthesis with Linkers Carrying Reactive Residues: I. The Synthesis of Deoxynucleoside Derivatives with Methoxyoxalamide Groups in Heterocyclic Bases |
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| Authors: | T V Abramova S V Vasil'eva T M Ivanova G V Shishkin V N Sil'nikov |
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| Institution: | (1) Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, pr. akademika Lavrent'eva 8, Novosibirsk, 630090, Russia |
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| Abstract: | A number of monomers for the standard phosphoamidite oligodeoxynucleotide synthesis that carry reactive methoxyoxalamide groups attached to the thymidine, 2 -deoxycytidine, and 2-deoxyadenosine heterocyclic bases were prepared. |
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| Keywords: | modified nucleosides linkers carrying reactive groups oligonucleotide synthesis |
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