Polysaccharides of Ganoderma lucidum: Factors affecting their production

The conditions of polysaccharide production by the fungus Ganoderma lucidum were optimized. The maximal yield of endopolysaccharides and exopolysaccharides was observed at 25–30°C, initial pH of culture medium 4.0–6.0, and at a C:N ratio of 18:1 and 25:1, respectively. The greatest yield of mycelium was reached at a more intensive aeration, and the maximal yield of polysaccharides was observed at a less intensive aeration. The optimal ratio between fungus growth and polysaccharide production was observed at 100 rpm and an aeration of 1.0– 1.5 1/1 medium·min.Translated from Prikladnaya Biokhimiya i Mikrobiologiya, Vol. 41, No. 2, 2005, pp. 194–199.Original Russian Text Copyright © 2005 by Babitskaya, Shcherba, Puchkova, Smirnov.