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Lanthanide chelates as new fluorochrome labels for cytochemistry
Authors:E J Soini  L J Pelliniemi  I A Hemmil?  V M Mukkala  J J Kankare  K Fr?jdman
Institution:Wallac Oy, Turku, Finland.
Abstract:Anti-rabbit IgG labeled with a new fluorescent europium chelate was used to localize rabbit IgG to human smooth muscle myosin in a histological section. The antibody labeled with the europium chelate could be viewed with a conventional fluorescence microscope with a steady-state light source. This result encourages the development of a time-resolved fluorescence microscope, because a significant improvement in the signal-to-noise ratio can be anticipated.
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