Lanthanide chelates as new fluorochrome labels for cytochemistry |
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Authors: | E J Soini L J Pelliniemi I A Hemmil? V M Mukkala J J Kankare K Fr?jdman |
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Institution: | Wallac Oy, Turku, Finland. |
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Abstract: | Anti-rabbit IgG labeled with a new fluorescent europium chelate was used to localize rabbit IgG to human smooth muscle myosin in a histological section. The antibody labeled with the europium chelate could be viewed with a conventional fluorescence microscope with a steady-state light source. This result encourages the development of a time-resolved fluorescence microscope, because a significant improvement in the signal-to-noise ratio can be anticipated. |
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