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细辛脑联合多索茶碱治疗慢性阻塞性肺病疗效观察
引用本文:杨国宏,张晓,王丽娜,刘乐斌.细辛脑联合多索茶碱治疗慢性阻塞性肺病疗效观察[J].现代生物医学进展,2011,11(16):3143-3145.
作者姓名:杨国宏  张晓  王丽娜  刘乐斌
作者单位:1. 解放军第四二二医院呼吸科 广东湛江 524009
2. 解放军海军92854部队医院 广东湛江 524009
摘    要:目的:观察细辛脑联合多索茶碱治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效。方法:将164例AECOPD患者随机分为观察组(82例)和对照组(82例),对照组予低流量吸氧、抗炎、抗感染、纠正水电解质紊乱等综合治疗,观察组在此基础上加用注射用细辛脑、多索茶碱静脉治疗。观察两组治疗前后症状、体征改善情况及血气分析变化。结果:观察组与对照组临床总有效率分别为93.9%、81.7%(P<0.05),观察组在发热、咳嗽咳痰、喘息症状消失时间,以及肺部罗音减少50%以上时间均显著短于对照组(P<0.01),在FEV1、FEV1/FVC、PEF、PaO2、PaCO2等指标也显著优于对照组(P<0.01)。结论:在常规治疗基础上加用细辛脑、多索茶碱可以有效提高AECOPD患者的临床疗效。

关 键 词:细辛脑  多索茶碱  慢性阻塞性肺疾病

Doxofylline plus Asaroneon for Chronic Obstructive Pulmonary Disease
YANG Guo-hong,ZHANG Xiao,WANG Li-na,LIU Le-bin.Doxofylline plus Asaroneon for Chronic Obstructive Pulmonary Disease[J].Progress in Modern Biomedicine,2011,11(16):3143-3145.
Authors:YANG Guo-hong  ZHANG Xiao  WANG Li-na  LIU Le-bin
Institution:1Δ) (1 Respiratory departmentof People’s Liberation Army 422 Hospital,Guang dong,Zhanjiang 524005;2 Liberation Army Navy 92854Hospital,Guang dong,Zhanjiang 524005)
Abstract:Objective:To observe the efficacy of doxofylline and asarone on treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 164 patients with AECOPD were randomly divided into two groups(82 cases) and control group(82 cases).The control group were treated with the low-flow oxygen,anti-inflammatory,anti-infective,correct water and electrolyte disturbance such as combined therapy.On the basis of the control group,the observation group were added with injection asarone a...
Keywords:Asarone  Doxofylline  Chronic obstructive pulmonary disease  
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