| 网织红细胞在消化道肿瘤化疗前后的变化及临床意义 |
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| 引用本文： | 谭明娟,梅燕萍,徐菲,黄晓沁,张军芳.网织红细胞在消化道肿瘤化疗前后的变化及临床意义[J].现代生物医学进展,2011,11(15):2883-2884,2861. |
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| 作者姓名： | 谭明娟 梅燕萍 徐菲 黄晓沁 张军芳 |
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| 作者单位： | 南京医科大学附属南京第一医院检验科,江苏南京,210006 |
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| 摘 要： | 目的:探讨采用网织红细胞监测消化道肿瘤患者化疗前、后骨髓造血功能恢复的临床价值。方法:采用SysmexXE2100全自动细胞分析仪对60例消化道恶性肿瘤患者化疗过程中白细胞数(WBC)、血小板(PLT)、网织红细胞百分率(RET%)、未成熟网织红细胞指数(IRF)进行动态监测。结果:化疗后骨髓造血功能受到抑制,RET%和IRF从化疗后第3天开始出现明显下降,差异有统计学意义(P<0.01),在化疗后第14天开始出现回升,其中IRF值较第7天显著升高,两者间差异具有统计学意义(P<0.01);WBC和PLT则于化疗后第7天出现明显下降,差异具有统计学意义(P<0.01),化疗后第21天开始出现回升。结论:未成熟网织红细胞指数是预测化疗后骨髓造血恢复的较敏感指标。
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| 关 键 词： | 网织红细胞 未成熟网织红细胞指数 消化道肿瘤 |
Variation of Reticulocytes in Patients with Gastrointestinal Cancer before and after Chemotherapy and Its Clinical Significance |
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| TAN Ming-juan,MEI Yah-ping,XU Fei,HUANG Xiao-qin,ZHANG Jun-fang.Variation of Reticulocytes in Patients with Gastrointestinal Cancer before and after Chemotherapy and Its Clinical Significance[J].Progress in Modern Biomedicine,2011,11(15):2883-2884,2861. |
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| Authors: | TAN Ming-juan MEI Yah-ping XU Fei HUANG Xiao-qin ZHANG Jun-fang |
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| Institution: | △(Department of laboratory medicine,Nanjing First Hospital Affiliated to NJMU,Nanjing,210006,Jiangsu,China) |
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| Abstract: | Objective:To detect the variation of reticulocytes in patients with gastrointestinal cancer before and after chemotherapy and its clinical significance.Methods:The reticulocytes were examined by automatic blood analyzer Sysmex XE22100 using the peripheral blood of 60 patients with gastrointestinal cancer before and after chemotherapy.Results:Bone marrow function was obviously suppressed after chemotherapy.On 3d after chemotherapy,RET%and IRF decreased gradually(P<0.05),on 14d after chemotherapy, RET%and IRF... |
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| Keywords: | Reticulocyte Immature reticulocyte index Malignant tumor |
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