SdrA,a New DeoR Family Regulator Involved in Streptomyces avermitilis Morphological Development and Antibiotic Production |
| |
| Authors: | Dana Ulanova Shigeru Kitani Eiichiro Fukusaki Takuya Nihira |
| |
| Institution: | International Center for Biotechnology, Osaka University, Osaka, Japana;Oceanography Section, Science Research Center, Kochi University, IMT-MEXT, Kochi, Japanb;Department of Biotechnology, Graduate School of Engineering, Osaka University, Osaka, Japanc;MU-OU Collaborative Research Center for Bioscience and Biotechnology, Faculty of Science, Mahidol University, Bangkok, Thailandd |
| |
| Abstract: | The SAV3339 (SdrA) protein of Streptomyces avermitilis, a member of the DeoR family of regulators, was assessed to determine its in vivo function by gene knockdown through the use of cis-encoded noncoding RNA and knockout of the sdrA gene. These analyses revealed that SdrA represents another class of Streptomyces regulator that controls morphological development and antibiotic production. |
| |
| Keywords: | |
|
|
