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Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus
Authors:George E. Gentsch  Thomas Spruce  Rita S. Monteiro  Nick D.L. Owens  Stephen R. Martin  James C. Smith
Affiliation:1. The Francis Crick Institute, Developmental Biology Laboratory, 1 Midland Road, London NW1 1AT, UK;2. The Francis Crick Institute, Structural Biology Science Technology Platform, 1 Midland Road, London NW1 1AT, UK
Abstract:
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  • Keywords:Brachyury  TALEN  null mutation  morpholino  dosage  off-target  splicing  immune response  GC content
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