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Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization
Authors:Curtis A Thorne  Ina W Chen  Laura E Sanman  Melanie H Cobb  Lani F Wu  Steven J Altschuler
Institution:1. Green Center for Systems Biology, Simmons Cancer Center, Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;2. Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA;3. Department of Cellular and Molecular Medicine, University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA
Abstract:
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  • Keywords:Wnt  BMP  intestine  organoid  homeostasis  crypt  proliferation  epithelium  feedback
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