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Apoptosis in Feline Panleukopenia Virus-Infected Lymphocytes |
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| Authors: | Yasuhiro Ikeda Junko Shinozuka Takayuki Miyazawa Kyoko Kurosawa Yoshihiro Izumiya Yorihiro Nishimura Kazuya Nakamura Jinshun Cai Kentaro Fujita Kunio Doi and Takeshi Mikami |
| Institution: | Departments of Veterinary Microbiology1. and Veterinary Pathology,2. Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan |
| Abstract: | Feline panleukopenia virus (FPLV) was shown to induce apoptosis to feline lymphoid cells and to reduce the expression of interleukin-2 receptor α on the cells. FPLV-induced apoptosis might be a key element in the pathophysiology of atrophy of lymphoid tissues associated with feline panleukopenia caused by FPLV. |
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