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Palladium-catalyzed multi-component synthesis of steroidal A- and D-ring fused 5,6-disubstituted pyridines under microwave irradiation |
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| Authors: | Kommuri Shekarrao Dipankar Nath Partha Pratim Kaishap Sanjib Gogoi Romesh C Boruah |
| Institution: | Medicinal Chemistry Division, North-East Institute of Science and Technology, Jorhat, Assam 785 006, India |
| Abstract: | The preparation of steroidal A-, D-ring fused 5,6-disubstituted pyridines and nonsteroidal substituted pyridines is described form Pd(OAc)2 catalyzed multi-component reaction of steroidal/nonsteroidal β-halovinyl aldehyde, alkyne and benzylamine in solvent-free condition under microwave irradiation. |
| Keywords: | Palladium"} {"#name":"keyword" "$":{"id":"k0010"} "$$":[{"#name":"text" "_":"Steroid pyridine Microwave Multicomponent reaction β-Bromovinyl aldehyde Benzyl amine |
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