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Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

Authors:	Corinne Ferrier Maurice Henry Joseph Haiser Peter James Turnbaugh

Institution:	1. FAS Center for Systems Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA

Abstract:	Download : Download high-res image (284KB) Download : Download full-size image Highlights? The gut microbiome is highly active, similar to nutrient-rich productive systems ? Firmicutes dominate the active and damaged subsets of the gut microbiome ? Both antibiotics and host-targeted drugs rapidly alter the active gut microbiome ? Xenobiotics induce genes for drug metabolism, drug resistance, and stress response

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