C-curve: A novel 3D graphical representation of DNA sequence based on codons |
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| Authors: | Nafiseh Jafarzadeh Ali Iranmanesh |
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| Institution: | 1. University of Medicine and Pharmacy “Carol Davilla”, Department of Pharmacology, Toxicology and Clinical Psychopharmacology, #8 Floreasca Street, Bucharest 014461, Romania;2. Babe?-Bolyai University, Faculty of Chemistry and Chemical Engineering, Department of Chemistry, Arany Janos Street, No 11, Cluj-Napoca 400028, Romania;3. University of Bucharest, Faculty of Chemistry, Department of Analytical Chemistry, Panduri Avenue, No. 90, Bucharest 050663, Romania;4. University of Medicine and Pharmacy Carol Davila, Faculty of Pharmacy, Department of Drug Industry and Pharmaceutical Biotechnology, Traian Vuia Street # 6, Bucharest 020956, Romania;5. National Research Institute of Police Science, 6-3-1, Kashiwanoha, Kashiwa, Chiba 277-0882, Japan |
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| Abstract: | In this paper, a novel 3D graphical representation of DNA sequence based on codons is proposed. Since there is not loss of information due to overlapping and containing loops, this representation will be useful for comparison of different DNA sequences. This 3D curve will be convenient for DNA mutations comparison specially. In continues we give a numerical characterization of DNA sequences based on the new 3D curve. This characterization facilitates quantitative comparisons of similarities/dissimilarities analysis of DNA sequences based on codons. |
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