On the incidence of blood group O and Gm(?1) phenotypes in patients with malignant melanoma |
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Authors: | H Walter R Brachtel Maria Hilling |
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Institution: | (1) Department of Biology, University of Bremen, D-2800 Bremen, Federal Republic of Germany;(2) Department of Dermatology, University of Mainz, D-6500 Mainz, Federal Republic of Germany |
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Abstract: | Summary Fifteen polymorphic systems of the blood (ABO, MNSs, Rhesus, P, Kell, Duffy, Kidd, Hp, Gc, Gm, Inv, aP, PGM1, EsD, and 6-PGD) were examined in 191 unrelated male and female patients suffering from malignant melanoma. These polymorphic systems were compared with the corresponding phenotype and gene frequencies of controls from the same geographical area (Rhineland-Palatinate). The only associations discovered were the ABO and Gm polymorphisms: The incidence of O and Gm(-1) phenotypes in patients is obviously higher than in controls. These observations agree with the findings in other population samples from Germany and Bulgaria. |
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