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Re-analysis of data and its integration
Authors:Jensen Lars Juhl  Steinmetz Lars M
Institution:European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
Abstract:To understand a biological process it is clear that a single approach will not be sufficient, just like a single measurement on a protein--such as its expression level--does not describe protein function. Using reference sets of proteins as benchmarks different approaches can be scaled and integrated. Here, we demonstrate the power of data re-analysis and integration by applying it in a case study to data from deletion phenotype screens and mRNA expression profiling.
Keywords:Benchmarking  Data integration  Network analysis  Gene expression  Deletion phenotype
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