Re-analysis of data and its integration |
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Authors: | Jensen Lars Juhl Steinmetz Lars M |
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Institution: | European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. |
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Abstract: | To understand a biological process it is clear that a single approach will not be sufficient, just like a single measurement on a protein--such as its expression level--does not describe protein function. Using reference sets of proteins as benchmarks different approaches can be scaled and integrated. Here, we demonstrate the power of data re-analysis and integration by applying it in a case study to data from deletion phenotype screens and mRNA expression profiling. |
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Keywords: | Benchmarking Data integration Network analysis Gene expression Deletion phenotype |
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