| 多反应变量重复测量的混合效应模型及其应用 |
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| 引用本文： | 任仕泉,陈峰.多反应变量重复测量的混合效应模型及其应用[J].生物数学学报,1999,14(2):229-234. |
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| 作者姓名： | 任仕泉 陈峰 |
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| 作者单位： | 四川大学管理科学系!成都610065(任仕泉)，南通医学院医学统计学教研室!南通226001(陈峰)，华西医科大学卫生统计学教研室!成都610041(杨树勤)，四川省卫生防疫站!成都610031(吴先萍) |
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| 摘 要： | 本文给出了多反应变量重复测量的协方差矩阵结构，探讨了用迭代广义最小二乘法来求解其带协变量和不带协变量的混合效应模型中固定效应和随机效应系数，并对１９９１年四川省高血压调查资料进行实例分析，得到其结论符合实际情况．
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| 关 键 词： | 多反应变量 重复测量 混合效应模型 迭代广义最小二乘法 |
Mixed Models for Repeated Measure Data with Multiple Responses and Their Application |
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| Ren Shiquan Chen Feng.Mixed Models for Repeated Measure Data with Multiple Responses and Their Application[J].Journal of Biomathematics,1999,14(2):229-234. |
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| Authors: | Ren Shiquan Chen Feng |
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| Abstract: | The covariance matrix of multivariate repeated measures is given. The estimators for the fixed and random coefficients are obtained by using the Iterative Generalized Least Squares method in the mixed models with and without covariates. An example analysis of hypertension survey data has showed that its conclusion concides with the active situation. |
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| Keywords: | Multiple response Repeated measures Mixed effect models Iterative generalized least squares method |
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