| Abstract: | These studies were carried out using chronically implanted thermode probes in conscious oxen at 15 degrees C air temperature. The probes were perfused with water either 4 degrees C above or 5 degrees C below resiting hypothalamic temperature and the thermoregulatory response measured by the change in auditory meatal temperature during the perfusion periods of 25 or 40 min duration, respectively. The anatomical position of the probes was known relative to the third cerebral ventricle in each animal. The thermosensitive area of the ox anterior hypothalamic/preoptic region was shown to be highly localized in a position corresponding to the posterior part of the area preoptica. The same area was responsible for both warm and cold sensitivity, the warm sensitivity being approximately three times greater than the cold. |
