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A new synthesis of furanoid fatty acids: isomerisation of hydroxy-cis-enynoic acids by alkali, and on argentous silica gel
Authors:E Crundwell  A L Cripps
Institution:School of Pharmacy, Portsmouth Polytechnic, Park Road, Portsmouth, England UK
Abstract:Novel hydroxy-cis-enynoic acids have been prepared. Those of type
/></figure>C(CH<sub>2</sub>)<sub>6</sub>CO<sub>2</sub>H have been found to cyclise to furanoid acids on treatment with alkali, or on chromatography on argentous silica gel. The hydroxy-<em>cis</em>-enynoic acids stimulate smooth muscle, the furanoid acids are not similarly active.</td>
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