Accumulation and dissemination of prion protein in experimental sheep scrapie in the natural host |
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| Authors: | Stephen J Ryder Glenda E Dexter Lindsay Heasman Richard Warner S Jo Moore |
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| Institution: | (1) OIE Reference Laboratory for Rabies, Community Reference Laboratory for Rabies, Community Reference Laboratory for Rabies Serology, AFSSA, WHO Collaborating Centre for Research and Management in Zoonoses Control, Malzeville, France;(2) WHO Collaborating Centre for the Characterization of Rabies and Related Rabies Viruses, Rabies and Wildlife Zoonoses Group, Veterinary Laboratories Agency, Weybridge, UK |
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| Abstract: | Background Since 1954, there have been in excess of 800 cases of rabies as a result of European Bat Lyssaviruses types 1 and 2 (EBLV-1, EBLV-2) infection, mainly in Serotine and Myotis bats respectively. These viruses have rarely been
reported to infect humans and terrestrial mammals, as the only exceptions are sheep in Denmark, a stone marten in Germany
and a cat in France. The purpose of this study was to investigate the susceptibility of foxes to EBLVs using silver foxes
(Vulpes vulpes) as a model. |
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