OrthoSelect: a protocol for selecting orthologous groups in phylogenomics |
| |
Authors: | Fabian Schreiber Kerstin Pick Dirk Erpenbeck Gert W?rheide and Burkhard Morgenstern |
| |
Institution: | (1) Abteilung Bioinformatik, Institut f?r Mikrobiologie und Genetik, Georg-August-Universit?t G?ttingen, Goldschmidtstr. 1, 37077 G?ttingen, Germany;(2) Department f?r Geo- und Umweltwissenschaften, Ludwig-Maximilians-Universit?t, Richard-Wagner-Str. 10, 80333 M?nchen, Germany |
| |
Abstract: | Background Phylogenetic studies using expressed sequence tags (EST) are becoming a standard approach to answer evolutionary questions.
Such studies are usually based on large sets of newly generated, unannotated, and error-prone EST sequences from different
species. A first crucial step in EST-based phylogeny reconstruction is to identify groups of orthologous sequences. From these
data sets, appropriate target genes are selected, and redundant sequences are eliminated to obtain suitable sequence sets
as input data for tree-reconstruction software. Generating such data sets manually can be very time consuming. Thus, software
tools are needed that carry out these steps automatically. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|