Quantitative and qualitative study of acrocentric associations in 109 normal subjects

Summary This study involving 109 normal subjects shows that the mean number of associations by cell seems to represent a biological constant which is not sex related and increases with age, especially after 33 years. From a qualitative point of view, the associations are not at random and their distribution varies from one individual to another. The tendency to associate is a characteristic of a given chromosome in a given individual.This study was supported by I.N.S.E.R.M. (C.R.L. No. 7510424).