A new antitumor nucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd), is a potent inhibitor of RNA synthesis. |
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Authors: | A Matsuda M Fukushima Y Wataya T Sasaki |
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Affiliation: | Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. matuda@pharm.hokudai.ac.jp |
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Abstract: | The antitumor activity, metabolism, and mechanism of action of a newly developed antitumor nucleoside, 1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd) are described. |
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